Cambridge Healthtech Institute’s Inaugural

Immunology for Biotherapeutics

Understanding and Manipulating the Immune System for Therapeutic Advantage

October 22, 2018


Many of the exciting developments in drug discovery and development today concern the immune response and its manipulation and control. Our understanding of immune involvement in therapeutic disorders and their treatment is developing all the time. T and B lymphocyte subsets, NK cells, macrophages, dendritic cells and cytokines are all involved in a complex manner, and interference with one could have disastrous consequences if not well understood. At this symposium, attendees will find out how to utilize the immune system and overcome inhibitory factors without overlooking potential safety issues.

Current Understanding of the Role of T Regulatory Cells and Their Modulation
Ethan Shevach, MD, Senior Investigator, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, NIH

The Basis of T Cell Activation at the Cell Surface with MHC Complexes
David Margulies, MD, PhD, Senior Investigator, Molecular Biology, NIAID/DIR

Applying Bispecific Technology to Modulate the Immune Response for Therapeutic Intervention
Paul Moore, PhD, Cell Biology & Immunology, Macrogenics, Inc.

Immunology Safety Considerations for Biotherapeutics
Rakesh Dixit, PhD, Vice President, R&D, Global Head, Biologics Safety Assessment, MedImmune, Inc.

Biopharmaceutical Product Immunogenicity: What Causes It and What Are the Safety and Efficacy Consequences?
Bonita (Bonnie) Rup, PhD, Biopharmaceutical Consultant, Bonnie Rup Consulting

Vaccines: Understanding the Mode of Action, Progress to Date, and Ongoing Challenges
Mike Lacy, PhD, Associate Director, Immunology, Emergent Biosolutions

For more details on the conference, please contact:
Nicole Lyscom, PhD
Senior Conference Director
Cambridge Healthtech Institute
Phone: +44 7791 866489

For partnering and sponsorship information, please contact:
Carolyn Benton
Business Development Manager
Cambridge Healthtech Institute
Phone: (+1) 781-972-5412